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. Author manuscript; available in PMC: 2011 Apr 25.
Published in final edited form as: Cancer Prev Res (Phila). 2010 Mar 16;3(4):466–477. doi: 10.1158/1940-6207.CAPR-09-0021

Table 1.

Effects of exercise with or without controlled dietary intake on the profiles of phospholipids in mouse skin tissues1

Phospholipid
Group
Species2 M/Z Mol% of Total Polar Lipids3

Sedentary Ex+AL Ex+PF

Phospho-coline 30:0 706.5 0.30±0.03a 0.28±0.03a 0.19±0.03b
32:0 734.6 2.21±0.34a 2.10±0.27a 1.02±0.13b
32:1 732.6 1.49±0.10a 1.18±0.12a 0.91±0.08b
40:4 838.6 0.16±0.01b 0.20±0.01ab 0.21±0.02a
40:5 836.6 0.39±0.00b 0.43±0.09b 0.81±0.13a
40:6 834.6 0.64±0.14ab 0.51±0.10b 1.03±0.17a

Phosphatidylinositol 36:1 863.6 0.02±0.01ab 0.07±0.04a 0.00±0.00b
36:2 861.5 0.04±0.02a 0.02±0.02a 0.01±0.01b
36:4 857.5 0.07±0.04a 0.03±0.02ab 0.00±0.00b
38:4 885.5 4.17±0.61a 3.10±0.41ab 2.66±0.32b
38:5 883.5 0.14±0.08ab 0.20±0.07b 0.02±0.01b

Ether phosphatidyl-
choline
32:0 720.6 0.26±0.06a 0.27±0.04a 0.12±0.03b
32:1 718.6 0.11±0.02a 0.11±0.02a 0.06±0.01b
32:2 716.6 0.03±0.01a 0.03±0.01a 0.01±0.00b
34:0 748.6 0.05±0.02a 0.04±0.01a 0.01±0.00b
34:1 746.6 0.40±0.07a 0.42±0.06a 0.21±0.03b
34:2 744.6 0.21±0.04ab 0.25±0.04a 0.13±0.02b
36:1 774.6 0.23±0.05a 0.33±0.05a 0.18±0.04b
36:2 772.6 0.22±0.05ab 0.34±0.06a 0.16±0.02b
36:3 770.6 0.08±0.02ab 0.10±0.02a 0.06±0.01b
36:4 768.6 0.17±0.03ab 0.16±0.02a 0.10±0.02b
36:5 766.6 0.15±0.02a 0.16±0.01a 0.11±0.01b
38:1 802.7 0.06±0.01ab 0.08±0.01a 0.04±0.01b
38:2 800.7 0.15±0.05b 0.36±0.07a 0.14±0.04b
38:3 798.6 0.03±0.01ab 0.06±0.01a 0.03±0.01b
38:4 796.6 0.14±0.01a 0.13±0.01a 0.09±0.01b
38:5 794.6 0.17±0.03ab 0.21±0.03a 0.12±0.02b
40:2 828.7 0.02±0.00b 0.04±0.01a 0.03±0.01b

Ether phosphor-
etherine
36:2 730.6 0.21±0.05b 0.44±0.08a 0.23±0.03b
38:2 758.6 0.05±0.01b 0.24±0.05a 0.09±0.02b
38:5 752.6 0.22±0.03ab 0.26±0.03a 0.19±0.02b

Lysophosphatidly-
choline
16:0 496.3 0.43±0.10a 0.36±0.03a 0.23±0.05b
18:1 522.4 0.16±0.03ab 0.20±0.04a 0.10±0.02b
18:2 520.3 0.17±0.05ab 0.22±0.04a 0.12±0.02b
20:4 544.3 0.08±0.02a 0.08±0.02a 0.04±0.01b

Lysophopho-
etherine
22:5 528.3 0.03±0.01ab 0.03±0.01b 0.07±0.01a
22:6 526.3 0.05±0.01b 0.05±0.01b 0.11±0.02a

Sphingomylin 16:0 703.6 2.36±0.51a 2.72±0.45a 1.14±0.25b
24:1 813.7 2.31±0.41ab 2.62±0.35a 1.73±0.26b
1

CD-1 mice were exercised with or without controlled dietary intake for 14 weeks. Quantitative profiling of detectable phospholipids in the mouse skin tissues was performed by electrospray ionization tandem mass spectrometry (ESI-MS/MS); Only the significantly changed phospholipids are shown.

2

Total acyl carbons:total double bonds;

3

Results are means ±SE, n=8–15 per group. Means with different letters differ significantly, p ≤ 0.05.