Table 1. βPAT-3 cytoplasmic tail residues are required for fertility, gonad morphogenesis and function, and tail morphogenesis.
Young adult animals were scored for fertility (% of animals bearing live progeny), DTC migration defects (% of incorrectly formed gonad arms), Emo (% of animals with endomitotic oocytes) and Abt (% of animals with abnormal tail morphology). Strains showing significant pair-wise differences from wild type (+) for each phenotype, based on the 95% confidence interval for proportions, are shown shaded in gray.
| Trait | + | β1C 23° | β1C 15° | TTAA | Y792F | Y804F | YYFF | FKVV | W784A |
|---|---|---|---|---|---|---|---|---|---|
| Fertility | 86% N=59 |
54% N=56 |
1% N=100 |
72% N=142 |
84% N=44 |
93% N=55 |
86% N=59 |
83% N=48 |
100% N=60 |
| DTC migration | 11% N=122 |
24% N=58 |
50% N=26 |
45% N=101 |
22% N=134 |
38% N=202 |
27% N=148 |
19% N=88 |
21% N=100 |
| Emo | 1% N=112 |
18% N=129 |
N.D. | 14% N=59 |
12% N=126 |
19% N=104 |
19% N=100 |
2% N=100 |
3% N=146 |
| Abt | 14% N=59 |
23% N=56 |
N.D. | 68% N=133 |
18% N=44 |
5% N=55 |
22% N=59 |
4% N=48 |
4% N=98 |