Table 4.

Multivariate survival analysis using Cox's proportional hazards model: estimated hazard ratios, 95% confidence interval (CI) and P-values of the hypothesis test about independence between factors and survival

Variable	HR	95% CI	P
LNR >0.25 vs. ≤0.25	3.16	1.16–8.62	0.024
R1 vs. R0	4.40	1.19–16.24	0.026
TNM stage	1.52	0.78–3.01	0.229
Macroscopic vascular invasion	0.83	0.27–2.47	0.741
Perineural invasion	0.31	0.79–1.27	0.105

LNR, lymph node ratio.