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| cell line | GI50 (nM) | MDR1/MRP activity | BCRP activity |
|---|---|---|---|
| MCF7 | <1 | − | + (subset of cellsb) |
| MCF10A | 3513 | − | − |
| HCT-15 | 42 | + | not determined |
| SW620 | 27 | − | − |
| MES.SA | >10 000 | − | not determined |
| MES.SA/MX2 | 3358 | + | not determined |
At least two independent experiments were performed for each data point.
<50% of MCF7 cells displayed BCRP activity.
