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Reactions catalyzed by copper amine oxidases are biogenesis (a) and catalysis (b). (a) The protein derived cofactor, 2,4,5-trihydroxyphenylalaninequinone (TPQ) is the product of biogenesis and generates the mature enzyme. P represents the rest of the polypeptide chain. (b) Catalysis is divided into two half-reactions, reductive and oxidative. R represents the moiety of the substrate amine, which varies from a hydrogen atom to a polypeptide.
