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. Author manuscript; available in PMC: 2012 Apr 5.
Published in final edited form as: Vaccine. 2011 Feb 5;29(16):3067–3073. doi: 10.1016/j.vaccine.2011.01.076

Figure 6.

Figure 6

Figure 6

Passively transferred CHIK 181/25 immune serum protects AG129 mice from infection with 104 PFU CHIK 181/25 virus. Pooled serum samples raised in A129 mice after ID injection with 104 PFU CHIK 181/25 vaccine were passively transferred IP (undiluted or diluted 1:10 in 150μl volume) in groups of 5 naïve adult AG129 mice. One day later all mice were injected ID with 104 PFU of CHIK 181/25 virus. Control mice received IP normal mouse serum (NMS). Following infection mice were monitored daily for survival (a) and morbidity (b and c).