Skip to main content
. Author manuscript; available in PMC: 2011 Apr 25.
Published in final edited form as: J Am Coll Cardiol. 2010 Apr 6;55(14):1476–1486. doi: 10.1016/j.jacc.2009.11.066

Figure 7. LV Periostin and MMP-2 Expression.

Figure 7

(A) AC6 deletion reduced LV expression (quantitative reverse transcriptase-polymerase chain reaction) of periostin. Two-way analysis of variance showed a significant AC6 effect (p < 0.05) for periostin mRNA expression; p value above bar from post-hoc testing (CON vs. KO, 3 weeks after TAC). (B) LV periostin protein (Western blotting) was reduced 3 weeks after TAC in AC6-deleted mice; p value above bar from Student t test (2-tailed). (C) LV matrix metalloproteinase (MMP)-2 mRNA expression (quantitative reverse transcriptase-polymerase chain reaction) increased 3 weeks after TAC from similar pre-TAC levels; no group differences were observed. Error bars = 1 SE; numbers in bars = group size. Abbreviations as in Figures 1, 2, and 6.