Table 3. Multivariate logistic regression models of predictors of (A) ever receiving HAART and (B) receiving HAART ≥95% of follow-up time in the Comprehensive Care Center study cohort.
A. Predictors of ever receiving HAART (N = 1730) | B. Predictors of receiving HAART ≥95% of follow-up timea (N = 1275) | |||||||||||
Covariate | Model 1b | Model 2b | Model 1 b | Model 2 b | ||||||||
OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | |
Age (per year) | 1.03 | 1.02–1.04 | <0.001 | 1.03 | 1.02–1.04 | <0.001 | 1.02 | 1.01–1.04 | <0.001 | 1.02 | 1.01–1.04 | 0.001 |
Baseline CD4+ T cell countb <200 cells/mm3 | 4.40 | 3.17–6.12 | <0.001 | 4.43 | 3.19–6.16 | <0.001 | 1.13 | 0.88–1.46 | 0.33 | 1.15 | 0.89–1.48 | 0.29 |
Baseline HIV-1 RNAc >5 log10 copies/mL | 1.67 | 1.12–2.34 | 0.003 | 1.68 | 1.20–2.35 | 0.003 | 0.63 | 0.48–0.82 | 0.001 | 0.62 | 0.47–0.81 | 0.001 |
Female sex | 1.27 | 0.96 1.69 | 0.10 | 1.22 | 0.92–1.63 | 0.17 | 0.75 | 0.57–0.99 | 0.05 | 0.71 | 0.53–0.94 | 0.02 |
Black race | 0.56 | 0.43–0.71 | <0.001 | 0.57 | 0.44–0.73 | <0.001 | 0.64 | 0.50–0.81 | <0.001 | 0.65 | 0.51–0.83 | 0.001 |
Follow-up time (per year) | 1.66 | 1.53–1.81 | <0.001 | 1.68 | 1.54–1.83 | <0.001 | 0.96 | 0.90–1.02 | 0.21 | 0.97 | 0.91–1.03 | 0.28 |
IDU history | 0.61 | 0.45–0.84 | 0.003 | 0.47 | 0.33–0.67 | <0.001 | 0.78 | 0.56–1.09 | 0.15 | 0.63 | 0.44–0.90 | 0.01 |
NIDU history b | - | - | - | 0.62 | 0.47–0.81 | 0.001 | - | - | - | 0.66 | 0.52–0.85 | 0.001 |
Among those ever exposed to HAART.
Model 1 did not include NIDU history, in order to be consistent with results of the corresponding model of JHU data. Model 2 included both IDU and NIDU, as well as the other covariates shown. IDU and NIDU were mutually exclusive definitions (see METHODS), thus Model 2 results do not denote independent relationships between drug-use categories and outcome variables.
CD4+ T cell counts and plasma HIV-1 RNA levels not available for all persons; data shown are for those persons with data available. Baseline laboratory values are defined as the first values obtained on or after the initial office visit, between January 1, 1999 and December 31, 2004.
HAART = highly active antiretroviral therapy; OR = odds ratio; CI = confidence interval; IDU = injection drug use; NIDU = non-injection drug use.