Figure 2. Meta-analysis of all studies with available data.
Meta-analysis of overall survival using hazard-ratio as effect measure after first-line HSCT vs. first-line IST. Pooled estimate not justified because of considerable heterogeneity and of not sufficient external validity. Abbreviations: HSCT: hematopoietic stem cell transplantation; IST: immunosuppressive therapy; SAA: severe aplastic anemia; SE: standard error.