Table 4. Treatment characteristics.
No | Study | HSCT; N. treated/N. total (%) | IST; N. treated/N. total (%) | ||
Irradiation* | ATG or ALG | ATG or ALG | CSA | ||
1 | Ahn 2003 [31] | 6/64 (9) | 53/64 (83) | 148/156 (95) | 67/156 (43) |
2 | Arranz 1994 [32] | 20/21 (95) | – | 29/29 (100) | 0 |
3 | Bacigalupo 1988 [33] | 110/218 (50) | – | 291/291 (100) | 0 |
4 | Bacigalupo 2000 [34] | 433/1759 (25) | 28/1759 (2) | – | – |
5 | Bayever 1984 [35] | 35/35 (100) | 0 | 22/22 (100) | 0 |
6 | Champlin 1984 [36] | 59/61 (97) | 0 | 69/69 (100) | 0 |
7 | De Planque 1990 [37] | 15/19 (79) | 1/19 (5) | 83/83 (100) | 0 |
8 | Doney 1997 [38] | 0 | 21/168 (24) | 225/227 (99) | 1/227 (1) |
9 | Fouladi 2000 [39] | 12/21 (57) | 5/21 (24) | 20/20 (100) | 19/20 (95) |
10 | Führer 1998 [40] | – | 28/28 (100) | 86/86 (100) | 86/86 (100) |
11 | Führer 2005 [41] | 0 | 0 | VSAA: 97/97 (100) | VSAA: 97/97 (100) |
SAA: 49/49 (100) | SAA: 49/49 (100) | ||||
12 | Ghavamzadeh 2004 [42] | 0 | 29/29 (100) | 2/24 (8) | 24/24 (100) |
13 | Gillio 1997 [43] | 17/25 (68) | 3/25 (12) | 23/23 (100) | 0 |
14 | Gluckman 1979 [44] | 10/37 (27) | 9/37 (24) | 28/28 (100) | 0 |
15 | Halperin 1989 [45] | 14/14 (100) | 14/14 (100) | 12/12 (100) | 0 |
16 | Kahn 2002 [46] | 8/15 (53) | 0 | 16/16 (100) | 16/16 (100) |
17 | Kim 2003 [47] | 17/22 (77) | 2/22 (9) | 74/74 (100) | 17/74 (23) |
18 | Kojima 2000 [48] | 26/37 (70) | 9/37 (24) | 27/63 (43) | 2/63 (3) |
19 | Lawlor 1997 [49] | 2/9 (22) | 1/9 (11) | 18/18 (100) | 15/18 (83) |
20 | Locasciulli 1990 [50] | 59/171 (35) | 34/171 (20) | 133/133 (100) | 0 |
21 | Locasciulli 2007 [51] | 282/1567 (18) | 319/1567 (20) | 495/912 (54) | 846/912 (93) |
22 | Paquette 1995 [52] | – | – | 1977–1983: 40/40 (100) | 0 |
1984–1989: 16/16 (100) | |||||
23 | Pitcher 1999 [53] | – | – | 1973–1988: 18/18 (100) | 1973–1988: 0 |
1989–1996: 25/25 (100) | 1989–1996: 14/25 (56) | ||||
24 | Tzeng 1989 [54] | 9/9 (100) | 0 | 7/7 (100) | 0 |
25 | Viollier 2005 [55] | – | – | 155/155 (100) | 0 |
26 | Werner 1989 [56] | 2/6 (33) | – | 8/9 (89) | 2/9 (22) |
*Irradiation: conditioning irradiation: thoraco-abdominal irradiation, total body irradiation, or total lymphoid irradiation.
Abbreviations: ALG: anti-lymphocyte globulin; ATG: anti-thymocyte globulin; CSA: cyclosporine A; HSCT: hematopoietic stem cell transplantation; IST: immunosuppressive therapy.