Table 3. Consistently enriched GO and KEGG categories.
ID | Category | Number of genes in category | 54 gene list | 124 gene list | 1475 gene list | |||
GO Biological Process (8 tools) | Tools | Genes | Tools | Genes | Tools | Genes | ||
GO:0008283 | cell proliferation | 1166 | 0 | - | 4 | 22 | 8 | 175 |
GO:0048518 | positive regulation of biological process | 2252 | 3 | 18 | 3 | 31 | 5 | 258 |
GO:0048522 | positive regulation of cellular process | 2050 | 3 | 18 | 3 | 30 | 5 | 243 |
GO:0042981 | regulation of apoptosis | 892 | 2 | 10 | 3 | 18 | 5 | 129 |
GO:0042127 | regulation of cell proliferation | 853 | 0 | - | 3 | 17 | 6 | 121 |
GO:0042221 | response to chemical stimulus | 1520 | 1 | 13 | 4 | 31 | 6 | 250 |
GO Molecular Function (7 tools) | ||||||||
GO:0015078 | hydrogen ion transmembrane transporter activity | 93 | 0 | - | 3 | 6 | 6 | 29 |
GO:0022890 | inorganic cation transmembrane transporter activity | 216 | 0 | - | 3 | 6 | 5 | 36 |
GO:0015077 | monovalent inorganic cation transmembrane transporter activity | 172 | 0 | - | 3 | 6 | 6 | 30 |
GO:0005515 | protein binding | 8184 | 3 | 38 | 5 | 80 | 6 | 843 |
GO:0051082 | unfolded protein binding | 113 | 4 | 4 | 1 | 4 | 7 | 30 |
KEGG pathway (7 tools) | ||||||||
KEGG4512 | ECM-receptor interaction | 58 | 2 | 2 | 3 | 5 | 4 | 24 |
KEGG4510 | focal adhesion | 135 | 2 | 3 | 2 | 5 | 5 | 49 |
KEGG5016 | Huntington's disease | 143 | 0 | - | 2 | 6 | 4 | 41 |
KEGG190 | oxidative phosphorylation | 203 | 1 | 2 | 5 | 7 | 4 | 33 |
KEGG5200 | pathways in cancer | 241 | 2 | 4 | 2 | 8 | 4 | 67 |
KEGG5012 | Parkinson's disease | 109 | 0 | - | 2 | 5 | 4 | 34 |
KEGG5222 | small cell lung cancer | 65 | 0 | - | 2 | 3 | 4 | 23 |
In each case, the number of enrichment tools reporting the category as significantly overrepresented and the maximal number of genes from the category present in the input gene list are indicated.