Table 3. Approximate output of urinary (rev/12 h) and fecal (rev/movement) mutagenicity.
Source | Study | Meat temperature | Un-hydrolyzed | Hydrolyzed |
Urine | Peters et al. (2004) | Low | 4, 537a | 51,527b |
High | 101,181a | 399,582b | ||
This studyc | Low | 32,000 | 101,000 | |
High | 95,000 | 553,000 | ||
High−inhibitors | 89,000 | 509,000 | ||
High+inhibitors | 57,000 | 891,000 | ||
Feces | This studyd | Low | 163,000 | 196,000 |
High | 147,000 | 643,000 | ||
High−inhibitors | 238,000 | 787,000 | ||
High+inhibitors | 94,000 | 565,000 |
Mean for 10 subjects.
Mean for 60 subjects.
Values converted from mean mutagenic potencies in rev/µmole creatinine (Fig. 2A and 2B) assuming 13964 µmole creatinine per 12 h urine sample. This conversion factor was a median based on 36 samples (4 samples each for 8 subjects; 1 sample each for 4 subjects) of first morning voids. Although we measured creatinine concentrations for all 64 samples (4 samples each from 16 subjects), we failed to record urine volume for 28 (4 samples each for 4 subjects plus 3 samples each for 4 subjects).
Values converted from mean mutagenic potencies in rev/mg lyophilized feces (Fig. 2C and 2D) assuming 19.32 g lyophilized feces per movement. This conversion factor was a median based on 32 fecal samples (2 samples each for 16 subjects).