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. 2011 Apr 25;6(4):e18907. doi: 10.1371/journal.pone.0018907

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Wang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Gene expression levels of key cytokines were adjusted against hARP across matching non-lesional, leading edge and lesional vitiligo skin pairs. (A) IFN-g and (B) IL-4 are hallmark cytokines for Th1 and Th2 polarization, respectively. (C) IL-17A and (D) IL-1ß serve as hallmark cytokines for Th17 polarization; Two way paired t-tests are performed for each data of gene expression data between non-lesional v.s. lesional, non-lesional v.s. leading-edge vitiligo skin. *p<0.05; **, p<0.01.