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. 2011 Apr 25;6(4):e18936. doi: 10.1371/journal.pone.0018936

Figure 6. Candidate Oncogenic miRNA enhance proliferation of melanoma cells.

Figure 6

(A) Verification of miR-17-5p over-expression in PAG transductants, as compared to mock-transduced cells. Y-axis denotes fold change above Mock-transduced cells. (B) Net proliferation of the PAG transductants was quantified with standardized XTT test. The number of cells was determined 48 h after seeding. The number of Mock-transductants was determined as 100%. Figure shows a representative experiment out of 3 performed. (C) Invasion activity of PAG transductants was quantified with 20 h-matrigel invasion assay, with correction for proliferation. Y-axis denotes the percentage of invaded cells. Figure shows a representative experiment out of three performed. ** denotes P<0.01 (2-tailed t-test).