Table 4.

Results of impulse response experiments in the perfused livers of young and old rats for sucrose and 100 nm microspheres. There were no significant differences between young and old for any parameter.

	Young (n=10)	Old (n=8)
Sucrose
Volume of distribution (ml/g)	10.9±3.1	14.4±7.9
Recovery (%)	90±15	86±10
CV2	0.74±0.13	0.84±0.47
Dispersion number	0.37±0.07	0.42±0.24
Microspheres
Volume of distribution (ml/g)	8.6±2.3	9.4±3.1
Recovery (%)	88±22	67±41
CV2	1.29±1.05	1.07±0.51
Dispersion number	1.00±0.27	0.77±0.44