Table 3.

Effects on the plasma ferric reducing/antioxidant power (FRAP), hepatic reduced glutathione content (GSH), and hepatic catalase activity (CAT) in mice pretreated with the hydroethanol crude extract (HCE) or the ethyl acetate fraction (f-EtOAc) from Bidens pilosa (15 mg/kg, p.o., 10 days), after CCl₄ on day 11 (0.5 ml/kg, i.p.), and controls

	Biomarkers of oxidative damage and antioxidant defenses
Group	FRAP (mM)	GSH (µmol/g)	CAT (mmol/min.g)
NC	21.7±0.7a	34.1±3.1a	163.7±29.6a
NEG	11.7±0.8	8.1±3.6	517.6±67.9
f-EtOAc	20.7±0.7a	30.1±0.4a	366.4±44.9a, b
HCE	18.9±0.9a	25.8±1.5a, b	447.1±33.1b
Silymarin	24.5±2.0a	29.8±4.2a	441.6±44.3b

Note: Values are expressed as means ± SD (n=6).

^aDenotes significant statistic differences at P<0.05 in comparison to the negative control group (NEG).

^bIn comparison to the normal control group (NC).