Table 3.
A: Pre-Treatment EGFR IHC Protein Expression Characteristics; B: EGFR IHC Protein Expression and Disease Status; C: Tabulation Between PFS > 6 months and Percent Staining
| IHC Measure | n | % | |
|---|---|---|---|
| Intensity | |||
| 1 | 14 | 30 | |
| 2 | 10 | 21 | |
| 3 | 23 | 49 | |
| P staining | |||
| High | 25 | 52 | |
| Low | 23 | 48 | |
| H-Value | |||
| High | 25 | 52 | |
| Low | 23 | 48 | |
| ADV N(%) |
RCS N(%) |
RCL N(%) |
||
|---|---|---|---|---|
| Intensity | ||||
| 1 | 3 (27) | 5 (25) | 6 (37) | |
| 2 | 1 (9) | 2 (10) | 7 (44) | |
| 3 | 7 (64) | 13 (65) | 3 (19) | |
| P Staining | ||||
| High | 7 (64) | 15 (71) | 3 (19) | |
| Low | 4 (36) | 6 (29) | 13 (81) | |
| H-Value | ||||
| High | 8 (73) | 14 (67) | 3 (19) | |
| Low | 3 (27) | 7 (33) | 13 (81) | |
| PFS> 6 | |||
|---|---|---|---|
| P Staining | Yes | No | |
| N (%) | N (%) | ||
| High | 5 (33) | 20 (60) | |
| Low | 10 (67) | 13 (40) | |
- ADV= advanced; ReCurrent Short (RCS) = Persistent or PFI ≤ median; ReCurrent Long (RCL) = PFI > median
- P Staining = dichotomy of percent staining at the median (0.81). If % staining ≥ 0.81, then P Staining =High.
- H-value = dichotomy of H score (percentage × intensity) at the median (1.44). If H-score ≥ 1.44, then H-Value= High.