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. Author manuscript; available in PMC: 2012 Apr 26.
Published in final edited form as: Curr Biol. 2011 Apr 7;21(8):635–644. doi: 10.1016/j.cub.2011.03.039

Figure 6. RhoC regulates cofilin phosphorylation at serine 3 through ROCK activation.

Figure 6

a) Western blot and quantification (b) of MTLn3 lysates from control or RhoC siRNA cells blotted for cofilin and pCofilinS3. Cells were starved for 3 h and stimulated with 5 nM EGF for 1 min. n = 3 independent experiments. c) Western blot and quantification (d) of MTLn3 lysates from cells transfected with RFP or RhoC-Q63L-RFP in the presence of vehicle control (DMSO) or the ROCK inhibitor (5 µM, H-1152) showing pCofilinS3 and cofilin levels. n = 3 independent experiments. p values are compared to RFP vehicle control **, p < 0.01.