Table 1.

The interaction profiles of six fragments with HIS in the top ranking positions.

Fragment ID	135		180		246		260		369		402
Structure
	HIS	1434	HIS	1173	HIS	2913	TRP	846	HIS	478	HIS	304
	TRP	923	TRP	153	ARG	903	HIS	521	THR	214	MET	217
	THR	321	TYR	151	GLY	513	TYR	272	GLN	125	TYR	151
	VAL	301	PRO	134	TRP	2692	PHE	238	VAL	111	LEU	134
	SER	219	GLY	125	CYS	1000	GLN	150	LEU	78	ILE	113
	MET	217	GLU	98	GLN	625	GLU	131	TRP	76	GLY	97
	PHE	214	ARG	96	PHE	571	MET	130	ALA	41	VAL	79
	LEU	146	ASP	80	SER	273	ILE	113	GLU	32	TRP	76
	LYS	125	PHE	71	GLU	311	LEU	112	TYR	30	ASP	60
	ASN	116	ALA	54	TYR	545	SER	109	PHE	23	ALA	41
	ARG	115	GLN	50	ALA	219	ASP	80	ASP	20	CYS	40
	GLY	97	MET	43	ASP	280	CYS	80			LYS	31
	ASP	80	CYS	40	MET	521	VAL	79			SER	27
	PRO	76	LEU	22	LEU	123	ALA	68			PHE	23
	GLN	75	ILE	18	ASN	232	PRO	38			THR	17
	TYR	60	SER	13	VAL	142	THR	35			GLU	16
	ILE	56			ILE	113	GLY	27
	GLU	49			LYS	93	ASN	23
	ALA	41			THR	107	ARG	19
					PRO	96