Skip to main content
. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Bioorg Med Chem Lett. 2010 Dec 1;21(9):2732–2735. doi: 10.1016/j.bmcl.2010.11.104

Scheme 3.

Scheme 3

Reagents: a) 3-pyrazoleboronic acid, Pd(PPh3)4, K2CO3, DMF, 100°C, 3h; b) MeI, K2CO3, DMF, 50°C, overnight; c) NBS, DMF, 50°C, 4h; d) R3B(OH)2, Pd(PPh3)4, K2CO3, DME/H2O, 100°C, 1h, microwave; e) R2PhNH2, HCl(1M)/H2O/dioxane (ratio 2/4/1).