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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Bioorg Med Chem Lett. 2010 Dec 1;21(9):2732–2735. doi: 10.1016/j.bmcl.2010.11.104

Table 3.

Inhibition of JNK3 by compounds 29–35.

Compds X R1 R2 JNK3 IC50 (μM)a p38 IC50 (μM)a
29 F Bn E 0.10 >20
30 F (CH2)2Ph E 0.17 > 20
31 F graphic file with name nihms277308t1.jpg E 0.32 >20
32 H 3-MeOPh D 0.65 > 20
33 H 3-CNPh D 0.24 >20
34 H 4-MeSPh D 1.33 >20
35 H 2-Py D 0.34 >20
a

Values are means of three experiments, All standard deviation ≤ 20%