Skip to main content
. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Bioorg Med Chem Lett. 2010 Dec 9;21(9):2697–2701. doi: 10.1016/j.bmcl.2010.12.015

Table 2.

Structures and activities of analogs 14.

graphic file with name nihms262400u2.jpg
Cmpd Ar/Het M1 EC50 (μM)a %ACh Maxa
14a graphic file with name nihms262400t1.jpg 3.21 102
14b graphic file with name nihms262400t2.jpg 2.19 90
14c graphic file with name nihms262400t3.jpg >10 -
14d graphic file with name nihms262400t4.jpg >10 -
14e graphic file with name nihms262400t5.jpg >10 -
14f graphic file with name nihms262400t6.jpg >10 -
14g graphic file with name nihms262400t7.jpg >10 -
14h graphic file with name nihms262400t8.jpg >10 -
a

Average of at least three independent determinations