Table 2. Effect of metformin on metabolic parameters in 16.5-month-old female mice.

Treatment	Age at the start of metformin treatment	Glucose, mmol/l	Total cholesterol, mmol/l	Triglycerides, mmol/l	Insulin, μUnits/ml
Control	-	7.3 ± 1.50	2.9 ± 1.06	1.5 ± 0.46	0.17 ± 0.12
Metformin	3 months	8.1 ± 0.64	2.7 ± 0.37	1.0 ± 0.03	0.49 ± 0.47
	9 months	7.9 ± 0.59	2.5 ± 0.27	0.9 ± 0.22	0.06 ± 0.05
	15 months	7.8 ± 0.78	2.6 ± 0.21	1.1 ± 0.08	0.19 ± 0.18