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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Glia. 2011 Jan 6;59(4):569–576. doi: 10.1002/glia.21125

Figure 5.

Figure 5

WT murine primary microglia were incubated with 20 μg/ml PIC starting at time 0 and medium concentrations of IL-6 and TNFα were determined at 18 hr. Exposure to ibuprofen (500 μM), NS-398 (50 μM), or DMSO vehicle began at time = −0.5 hr and continued throughout the experiment. Shown are average percent ± SEM (n=3) of vehicle treated controls. One-way ANOVA was performed on concentration data for each analyte. ANOVA for IL-6 had P < 0.0005 and TNFα had P < 0.001 for the three groups. Bonferroni-corrected post tests had *P < 0.001 compared to vehicle. Results for each analyte were not significantly different (P > 0.05) between Ibuprofen and NS-398 groups.