Skip to main content
. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Lab Invest. 2010 Aug 9;90(12):1794–1804. doi: 10.1038/labinvest.2010.143

Figure 5. Effect of MCP-1-deficiency on levels of profibrogenic genes in the livers of mice fed the MCD diet.

Figure 5

MCP-1-deficient and wild type mice, both on the C57Bl/6J genetic background, were fed either control diet or MCD diet for 28 days. Hepatic levels of (A) Col1a1, (B) CTGF, (C) TGFβ, and (D) TIMP-1 were quantified. Data are expressed as mean ± SEM. N = 4 wild type mice fed control diet, 3 MCP-1−/− mice fed control diet, 8 wild type mice fed MCD diet, and 6 MCP-1−/− mice fed MCD diet. *Significantly different from mice of the same genotype fed control diet. #Significantly different from wild type mice fed the MCD diet.