Table 3.
Grade 3-4 NCI-CTC toxicities in 104 enrolled patients
| Arm A (EV = 54) | Arm B (PLD/V = 50) | |||
|---|---|---|---|---|
| No. | % | No. | % | |
| Anemia | 5 | 9.2 | 4 | 8 |
| Neutropenia | 10 | 18.5 | 11 | 22 |
| Thrombocytopenia | 1 | 1.8 | - | - |
| Febrile neutropenia | 3 | 5.5 | 1 | 2.0 |
| Hepatotoxicity | 2 | 3.7 | 2 | 4.0 |
| Mucositis | 4 | 7.4 | 6 | 12 |
| PPE/skin | - | - | 3 | 6 |
| Alopecia | 54 | 100 | 25 | 50 |
| Neurologic | 1 | 1.8 | 1 | 2.0 |
| Cardiac | 2 | 3.7 | - | - |
Abbreviations: NCI-CTC: National Cancer Institute Common Toxicity Criteria; PPE: palmoplantar erithrodysthesia; EV: epirubicin/vinorelbine; PLD/V: pegylated liposomal doxorubicin/vinorelbine