Fig. 2.
AMH signaling regulates Wnt4 expression in the mouse Müllerian duct mesenchyme. Differential interference contrast images of Wnt4 expression in the developing reproductive tract from AMH signaling mutants detected by in situ hybridization at E13.5. (A,B) The reproductive tract of Amhr2+/− (A) and Amhr2−/− (B) XY males. (C,D) The reproductive tract of wild-type (C) and Mt-hAMHtg/+ (D) XX females. Black arrows and white arrowheads indicate the Müllerian duct mesenchyme and Wolffian duct epithelium, respectively. Dashed circles indicate the epithelium of the reproductive tracts.