Fig. 6.

β-catenin is required for Müllerian duct regression. (A-L) Reproductive organs from wild-type (A,E,I), Amhr2^Cre/+; Ctnnb1^flox/del (B,F,J), Amhr2^−/− (C,G,K) and Wnt7a^−/− (D,H,L) XY males at birth. A-D show whole-mount view of male reproductive organs; E-H are higher magnification images of the reproductive tract indicated by black arrows in A-D, respectively. I-L show histological analysis of the reproductive tract by Hematoxylin and Eosin staining. The asterisk in I indicates the region where the Müllerian duct regressed. Black arrows, white arrows and white arrowheads indicate the reproductive tract, Müllerian duct epithelium and Wolffian duct epithelium, respectively. e, epididymis; t, testis.