Table 2.
Cell type | Human adult stem cella | Human embryonic stem cellsa |
---|---|---|
Ease of isolation | Difficult | Easy, however, blastocyst may be destroyed |
Potency | Multipotent (lose pluripotent ability) | Pluripotent (infinite life span theoretically) |
Telomerase level | Low | High |
Chromosomes | Tend to be shortened with aging | Maintain through serial passages |
Apoptosis | Early | Late |
Teratoma risk | No | Yes |
Possibility of immune rejection | No | Yes |
Ethical issues | No | Yes |
Reference 30.