Table I.
Genes differentially up-regulated by CD4 T cells experiencing Ag derived from tumor (ProHA × TRAMP) or self (C3HAhigh)
| Probe Set IDa | Gene Symbol | Gene Title | ProHA × TRAMP | C3-HA | Fold Change |
|---|---|---|---|---|---|
| 1417409_at | Jun | Jun oncogene | 809 | 38 | 21.5 |
| 1453840_at | Pabpc1 | Poly(A)b-binding protein, cytoplasmic 1 | 1075 | 83 | 13.0 |
| 1455805_x_at | FoxP3 | Forkhead box P3 | 340 | 32 | 10.5 |
| 1436222_at | Gas5 | Growth arrest-specific 5 | 357 | 37 | 9.8 |
| 1440169_x_at | Ifnar2 | IFN (α and β) receptor 2 | 497 | 55 | 9.0 |
| 1456956_at | Zfn1a2 | Zinc finger protein, subfamily 1A, 2 | 859 | 103 | 8.4 |
| 1439036_a_at | Atp1b1 | ATPase, Na +/K +-transporting, β1 polypeptide | 125 | 15 | 8.1 |
| 1448208_at | Madh1 | MAD homolog 1 | 206 | 26 | 7.8 |
| 1427275_at | Smc4I1 | SMC4 structural maintenance of chromosomes 4-like 1 | 1290 | 186 | 7.0 |
| 1440770_at | Bcl2 | B cell leukemia/lymphoma 2 | 686 | 100 | 6.9 |
| 1438941_x_at | Ampd2 | AMP deaminase 2 | 722 | 105 | 6.9 |
| 1450339_a_at | Bcl11b | B cell leukemia/lymphoma 11B | 2529 | 369 | 6.9 |
| 1441926_x_at | Tmie | Transmembrane inner ear | 705 | 107 | 6.6 |
| 1437163_x_at | Gtf2h4 | General transcription factor II H, polypeptide 4 | 312 | 48 | 6.5 |
| 1417679_at | Gfi1 | Growth factor-independent 1 | 855 | 135 | 6.3 |
| 1428463_a_at | Ppp2r5e | Protein phosphatase 2, regulatory subunit B (B56), ε isoform | 128 | 20 | 6.3 |
| 1440104_at | Ranbp2 | RAN-binding protein 2 | 674 | 107 | 6.3 |
| 1440837_at | H2-Ob | Histocompatibility 2, O region β locus | 219 | 35 | 6.3 |
| 1436804_s_at | Scyl1 | SCY1-like 1 | 250 | 40 | 6.3 |
| 1419810_x_at | Gli | GLI-Kruppel family member GLI | 1392 | 227 | 6.1 |
| 1434895_s_at | Ppp1r13b | Protein phosphatase 1, regulatory (inhibitor) subunit 13B | 720 | 118 | 6.1 |
| 1448325_at | Myd116 | Myeloid differentiation primary response gene 116 | 2204 | 363 | 6.1 |
| 1450095_a_at | Acyp1 | Acylphosphatase 1, erythrocyte (common) type | 133 | 22 | 6.0 |
| 1456467_s_at | Nik | Nemo-like kinase | 314 | 53 | 5.9 |
| 1448471_a_at | Tpbpb | Trophoblast-specific protein β | 737 | 125 | 5.9 |
| 1437828_s_at | Bing4 | BING4 protein | 415 | 71 | 5.9 |
| 1427186_a_at | Mef2a | Myocyte enhancer factor 2A | 187 | 32 | 5.9 |
| 1425514_at | Pik3r1 | PI3K, regulatory subunit, polypeptide 1 | 156 | 27 | 5.7 |
| 1439768_x_at | Sema4f | Sema domain, Ig domain, TM domain, and short cytoplasmic domain | 419 | 74 | 5.7 |
| 1438259_at | Strn3 | Striatin, calmodulin-binding protein 3 | 328 | 58 | 5.6 |
| 1417734_at | Nakap95 | Neighbor of A kinase-anchoring protein 95 | 891 | 160 | 5.6 |
| 1439440_x_at | Ptk 9I | Protein tyrosine kinase 9-like | 1344 | 246 | 5.5 |
| 1437667_a_at | Bach2 | BTB and CNC homology 2 | 1291 | 237 | 5.4 |
| 1434399_at | Galnt6 | UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 | 1516 | 278 | 5.4 |
| 1440885_at | Evl | Ena-vasodilator-stimulated phosphoprotein | 909 | 168 | 5.4 |
| 1447757_x_at | Inpp5f | Inositol polyphosphate-5-phosphatase F | 180 | 34 | 5.3 |
| 1418643_at | Tm4sf13 | Transmembrane 4 superfamily member 13 | 5332 | 1004 | 5.3 |
| 1436983_at | Crebbp | CREB-binding protein | 673 | 127 | 5.3 |
| 1430357_at | H3f3b | H3 histone, family 3B | 527 | 100 | 5.3 |
| 1438211_s_at | Dbp | D site albumin promoter-binding protein | 382 | 73 | 5.2 |
a
ID, identification number; poly(A), polyadenylate; RAN, Ras-related nuclear protein; GLI, gliotactin; sema, semaphorin; TM, transmembrane; BTB, bric-a-brac, tramtrack, and broad complex; CNC, canary complex; Ena, enabled.