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. Author manuscript; available in PMC: 2011 Apr 26.
Published in final edited form as: Methods Mol Biol. 2009;502:91–111. doi: 10.1007/978-1-60327-565-1_7

Table 7.1.

Termini of tailed-phage virion DNAs.

Terminus type Prototype phage Replication strategy
Cohesive ends
   5′-single-strand extension λ P2 Rolling circle→concatemer
Circle→circle
   3′-single-strand extension HK97 Rolling circle→ concatemer*
Circularly permuted direct terminal repeats
T4 Complex→concatemer
P22 Rolling circle→concatemer
P1 Rolling circle→concatemer
Host DNA at termini
Mu Duplicative transposition into host DNA
Exact direct terminal repeats
   Short (few hundred base pairs) T7 Linear→concatemer
   Long (thousands of base pairs) SPO1 Complex→concatemer
T5 Complex→concatemer
Covalent terminal protein
ϕ29 Protein-primed linear→linear

Individual virions of these phages have chromosomes that terminate at many different places on the genome sequence, and the length of the terminal repeat varies among individual virions (see text).

*

Genomic analysis predicts this mode of replication, but it has not been studied experimentally.