TABLE 1.

Summary table for modeled clearance values

Clearances are expressed as l · h⁻¹ · kg⁻¹.

Parameter	Well Stirred		Parallel Tube
	Allometric	Simcyp	Allometric	Simcyp
UGT1A1 clearance
Normalized adult clearance	0.0070	0.0079	0.0070	0.0079
R2	0.0131	0.0077	0.0131	0.0076
95% CI of adult clearance	0.0058, 0.0082	0.0063, 0.0095	0.0058, 0.0082	0.0063, 0.0095
Age within 90% of adult	3.0 years	2.6 years	2.8 years	2.5 years
Weighted sum-of-squares	0.0034	0.0058	0.0035	0.0059
Sy.x	0.0049	0.0064	0.0049	0.0064
UGT1A6 clearance
Normalized adult clearance	Not converged	0.3524	Not converged	Ambiguous
R2		0.0686
95% CI of adult clearance		0.3149, 0.3900
Age with 90% of adult		12.6 months
Weighted sum-of-squares		2.182
Sy.x		0.1548