Table 3.
Difference in estimated GFR by the MDRD and CKD-EPI at the time of CKD
| Patient Characteristics | Average Difference (± SD) in eGFR in ml/min per 1.73 m2 (CKD-EPI − MDRD)a | Percentage of Patients with eGFR on the Basis of CKD-EPI ± 5 ml/min per 1.73 m2 Different from eGFR on the Basis of MDRD | Percent of Patients with eGFR on the Basis of CKD-EPI ≥10% Different from eGFR on the Basis of MDRD |
|---|---|---|---|
| Age 18 to 59 (n = 7379) | 2.84 ± 1.84 | 8.8 | 5.8 |
| Age 60 to 69 (n = 10,982) | 1.43 ± 1.34 | 0 | 0.6 |
| Age 70 to 79 (n = 15,688) | −0.33 ± 1.14 | 0 | 1.1 |
| Age 80 to 89 (n = 12,033) | −1.89 ± 1.07 | 1.3 | 4.4 |
| Age 90+ (n = 1726) | −3.60 ± 1.17 | 9.4 | 26.7 |
| African American (n = 6095) | −1.51 ± 2.10 | 5.3 | 14.3 |
| Non-African American (n = 41,713) | 0.28 ± 2.11 | 2.0 | 2.4 |
| Diabetes present (n = 10,213) | 0.09 ± 2.07 | 1.8 | 3.2 |
| Diabetes absent (n = 37,595) | 0.04 ± 2.23 | 2.6 | 4.0 |
| Male gender (n = 21,745) | −0.42 ± 2.07 | 1.6 | 4.0 |
| Female gender (n = 26,063) | 0.45 ± 2.22 | 3.1 | 3.7 |
| BMI <20 kg/m2 (n = 1656) | −0.33 ± 2.46 | 4.7 | 8.5 |
| BMI 20 to 24 kg/m2 (n = 9935) | −0.36 ± 2.27 | 3.0 | 5.3 |
| BMI 25 to 29 kg/m2 (n = 15,905) | −0.12 ± 2.10 | 2.0 | 3.1 |
| BMI 30 to 34 kg/m2 (n = 9528) | 0.37 ± 2.07 | 2.1 | 2.6 |
| BMI 35 + kg/m2 (n = 6930) | 1.08 ± 2.02 | 2.5 | 2.3 |
| BMI missing (n = 3854) | −0.60 ± 2.15 | 2.5 | 6.5 |
| Primary insurance: Medicare (n = 28,165) | −0.50 ± 1.90 | 1.3 | 4.0 |
| Primary insurance: Medicaid (n = 832) | 1.59 ± 2.31 | 7.1 | 7.6 |
| Primary insurance: other/unknown (18,811) | 0.81 ± 2.34 | 3.6 | 3.4 |
| Overall (n = 47,808) | 0.05 ± 2.20 | 2.4 | 3.8 |
The classification of CKD was on the basis of the CKD-EPI equation.
a
Negative values indicate lower GFR with the CKD-EPI equation.