Table 3.
Simple (left) followed by backward stepwise multiple logistic regression analyses (R2 = 0.40) demonstrating independent associations with of abnormal MTWA result
| Variable | Univariate Analyses |
Multivariate Analyses |
||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | |
| Age (per year) | 1.04 | 1.02, 1.07 | <0.01 | 1.04 | 1.01, 1.07 | 0.01 |
| IHD | 6.19 | 2.74, 13.94 | <0.01 | 3.24 | 1.31, 8.02 | 0.01 |
| Cerebrovascular disease | 6.83 | 1.98, 23.60 | <0.01 | 5.81 | 1.56, 12.87 | <0.01 |
| Peripheral vascular disease | 7.47 | 2.53, 22.11 | <0.01 | 5.34 | 1.68, 16.96 | <0.01 |
| LVMI (per g/m2) | 1.01 | 1.00, 1.02 | 0.01 | 1.02 | 1.01, 1.02 | 0.02 |
| LV dilation | 7.20 | 1.62, 32.07 | 0.01 | 4.34 | 0.98, 21.90 | 0.06 |
| Glucose (per mmol/L) | 1.10 | 1.02, 1.19 | 0.01 | |||
| EF (per %) | 0.98 | 0.95, 0.98 | 0.01 | |||
| Diabetes mellitus | 2.12 | 1.09, 4.15 | 0.03 | |||
| Hypercholesterolemia | 1.92 | 1.08, 3.40 | 0.03 | |||
| RRT | ||||||
| predialysis | 1.00 | |||||
| peritoneal dialysis | 0.57 | 0.19, 1.70 | 0.31 | |||
| hemodialysis | 1.93 | 1.05, 3.59 | 0.04 | |||
| RRT time (per year) | 1.10 | 0.91, 1.33 | 0.30 | |||
| Gender (male versus female) | 1.06 | 0.59, 1.90 | 0.84 | |||
| BMI (per kg/m2) | 0.97 | 0.92, 1.03 | 0.36 | |||
| Systolic BP (per mmHg) | 1.01 | 0.99, 1.02 | 0.07 | |||
| Diastolic BP (mmHg) | 0.97 | 0.95, 1.00 | 0.06 | |||
| Pulse pressure | 1.02 | 0.99, 1.03 | 0.07 | |||
| Chronic heart failure | 2.14 | 0.65, 6.97 | 0.21 | |||
| Smoking | ||||||
| never | 1.00 | |||||
| current/former | 1.73 | 0.88, 3.47 | 0.12 | |||
| Hemoglobin (per g/dl) | 1.02 | 0.86, 1.18 | 0.96 | |||
| Fibrinogen (per g/L) | 0.92 | 0.70, 1.23 | 0.58 | |||
| ESR (per mm/h) | 0.99 | 0.98, 1.01 | 0.83 | |||
| CRP (per mg/L) | 1.01 | 0.99, 1.02 | 0.62 | |||
| Adjusted calcium (per mmol/L) | 1.08 | 0.41, 2.85 | 0.86 | |||
| Phosphate (per mmol/L) | 0.60 | 0.34, 1.07 | 0.08 | |||
| PTH (per pmol/L) | 0.99 | 0.98, 1.01 | 0.42 | |||
| HbA1c (per %) | 0.99 | 0.98, 1.01 | 0.48 | |||
| Potassium (per mmol/L) | 0.94 | 0.63, 1.40 | 0.76 | |||
| Cholesterol (per mmol/L) | 0.60 | 0.32, 1.17 | 0.13 | |||
| Triglyceride (per mmol/L) | 1.12 | 0.69, 1.81 | 0.67 | |||
| HDL-cholesterol (per mmol/L) | 1.34 | 0.70, 2.57 | 0.38 | |||
| LDL-cholesterol (per mmol/L) | 1.17 | 0.63, 2.16 | 0.62 | |||
| Creatinine (per μmol/L) | 0.99 | 0.99 to 1.00 | 0.33 | |||
| EDV/BSA (ml/m2) | 1.00 | 0.98, 1.02 | 0.64 | |||
| ESV/BSA (ml/m2) | 1.02 | 0.98, 1.04 | 0.21 | |||
| LVSD | 1.87 | 0.93, 3.79 | 0.08 | |||
| CAD | ||||||
| obstructive CAD (reference) | 1.00 | |||||
| normal/nonobstructive | 2.08 | 0.53 to 6.60 | 0.23 | |||
Only variables found to be significant on univariate analyses were entered into the multivariate model. OR, odds ratio; CI, confidence interval; PTH, parathyroid hormone; HbA1c, hemoglobin A1c.