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. 2011 Apr 26;6(4):e18673. doi: 10.1371/journal.pone.0018673

Table 2. Putative virulence genes associated with complicated infections.

Clinical Outcome
Common Gene Name Locus Source Strain Sum Hitsa Array P-value For Associationb PCR P-value For Associationc P-value After Adjust for MRSAd Simple Agreement
transposase/integrase VRA0002 Michigan-VRSA 13 0.0008 0.0007 0.5604 0.927*
transposase/integrase SA1483 N315 3 0.0004 <0.0001 0.0332 0.899*
thymidylate synthase VRA0005 Michigan-VRSA 1 0.0147 0.152 0.6199 0.89*
hypothetical phage protein SAS0928 MSSA476 1 0.0127 0.0018 0.2105 0.99*
prophage amidase/cell wall autolysin SA0389 COL 2 0.0112 0.0019 0.4321 0.867*
conserved hypothetical protein SA0329 COL 1 0.0205 0.1916 0.4568 0.838*
hypothetical phage protein SAR1546 MRSA252 2 0.0227 0.0001 0.0261 0.581
hypothetical phage protein SAR1502 MRSA252 1 0.0131 0.0019 0.1661 0.768*
prophage amidase/cell wall autolysin MW1380 MW2 2 0.0124 0.0029 0.2461 0.853*
phage regulatory protein SAR1522 MRSA252 4 0.002 n.d. n.d. n.d.
hypothetical protein MW1385 MW2 2 0.0022 0.0011 0.1764 0.994*
conserved hypothetical protein SA0338 COL 1 0.0085 <0.0001 0.0132 0.988*
hypothetical protein SA0397 N315 3 0.0049 0.0219 0.4199 0.755*
putative regulatory protein SAR1555 MRSA252 1 0.0146 0.0079 0.7332 0.908*

(a)Sum Hits: the number of times this probe hybridized to a part of the sequenced genomes.

(b)P-value for clinical association from aCGH results.

(c)P-value for clinical association from PCR validation.

(d)P-value for gene association with sick outcome after adjusting for MRSA status.

*Value greater than 0.60 indicates PCR results are in simple aggrement with a CGH results.