Table 1.
Demographic, clinical and pathologic information of patients in the JHH and UCHE cohorts.
| Variable | JHH | UCHE | P-value* |
|---|---|---|---|
| (N = 5730) | (N = 1646) | ||
| Age (years) | 57.4 ± 6.4 | 61.9 ± 5.7 | <2.2e-16 |
| PSA (ng/ml) | <2.2e-16 | ||
| <=2.5 | 452 (7.9) | 67 (4.1) | |
| 2.6 - 4.0 | 946 (16.5) | 211 (12.8) | |
| 4.1 - 6.0 | 1994 (34.8) | 434 (26.4) | |
| 6.1 - 8.0 | 1093 (19.1) | 354 (21.5) | |
| 8.1 - 10 | 578 (10.1) | 199 (12.1) | |
| >10 | 667 (11.6) | 381 (23.1) | |
| Clinical Stage | 8.1e-6 | ||
| T1c | 4419 (77.1) | 1207 (73.3) | |
| T2a | 998 (17.4) | 297 (18.0) | |
| T2b/c | 313 (5.5) | 142 (8.7) | |
| Biopsy Gleason score (%) | <2.2e-16 | ||
| <7 | 4402 (76.8) | 1059 (64.3) | |
| 3+4 =7 | 816 (14.2) | 403 (24.5) | |
| 4+3 = 7 | 348 (6.1) | 127 (7.7) | |
| >7 | 164 (2.9) | 57 (3.5) | |
| Organ confined (%) | 0.531 | ||
| Yes | 4204 (73.4) | 1221 (74.2) | |
| No | 1526 (26.6) | 425 (25.8) | |
| Extraprostatic extension (%) | 1.7e-6 | ||
| No | 4454 (77.7) | 1370 (83.2) | |
| Yes | 1276 (22.3) | 276 (16.8) | |
| Seminal vesicle involvement (%) | 5.9e-11 | ||
| No | 5550 (96.9) | 1535 (93.3) | |
| Yes | 180 (3.1) | 111 (6.7) | |
| Lymph node involvement (%) | 0.0018 | ||
| No | 5660 (98.8) | 1608 (97.7) | |
| Yes | 70 (1.2) | 38 (2.3) | |
*
p-value comparing JHH and UCHE based on two-sample t-test for continuous covariates and based on Chi-square test for discrete covariates