Table 2.
Small molecules for enhanced reprogramming efficiency
| Molecule | Name | Target | Reference |
|---|---|---|---|
 |
Valproic Acid (VPA) | Histone deacetylase (HDAC) Inhibitor |
Huangfu (2008) |
 |
BIX01294 | AG9a histone methyltransferase (HMTase) inhibitor |
Shi (2008b) |
 |
RG108 | DNA methyltransferase (DNMT) Inhibitor |
Shi (2008a) |
 |
BayK8644 | L-type calcium channel agonist |
Shi (2008a) |
 |
RepSox | TGFβ inhibitor | Ichida (2009) |
 |
SB431542 | TGFβ inhibitor |
Lin (2009) Chambers (2009) |
 |
Parnate | lysine-specific demethylase 1 (LSD1) inhibitor |
Li (2009a) |
 |
Sodium Butyrate (NaB) | Histone Deacetylase (HDAC) inhibitor |
Zhu (2010) |
 |
PS48 | PDK1 activator | Zhu (2010) |
 |
Reversine | Aurora B Kinase Inhibitor |
Chen (2004) D'Alise (2008) |