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. 2011 Apr 21;17(15):2019–2027. doi: 10.3748/wjg.v17.i15.2019

Table 1.

Serum levels of transforming growth factor-β1 and the population of CD4+Foxp3+ Tregs in patients with gastric cancer according to clinicopathological findings

Variables n TGF-β1 (ng/mL) P Tregs (%) P
Gender > 0.05 > 0.05
Male 38 16.1 ± 6.8 8.0 ± 3.2
Female 18 14.0 ± 5.1 7.6 ± 2.5
Age > 0.05 > 0.05
< 55 25 14.1 ± 4.1 8.2 ± 4.1
> 55 31 15.9 ± 4.6 7.7 ± 3.5
TNM stage < 0.05 < 0.05
Early stage (I/II) 22 12.4 ± 5.0 6.3 ± 1.2
Advanced stage (III/IV) 34 18.1 ± 7.8 8.8 ± 2.4
Histological type > 0.05 > 0.05
Well and Moderately 20 14.1 ± 4.9 7.0 ± 3.7
Poor 36 16.8 ± 7.9 8.6 ± 4.5
Lymph node metastasis < 0.05 < 0.05
Negative 18 11.2 ± 5.2 6.5 ± 2.4
Positive 38 17.4 ± 7.2 8.6 ± 2.9

TGF: Transforming growth factor; Tregs: Regulatory T cells.