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. Author manuscript; available in PMC: 2011 Apr 27.
Published in final edited form as: Chem Res Toxicol. 2008 Aug 26;21(10):1991–1996. doi: 10.1021/tx800210k

Table 1.

Sensitivity and Range of Analysis for the HPLC-MS/MS Analysis of SFN Conjugates in Urine

compound limit of detection (pg) range of sample volumes used (μL of urine) limit of determination (ng/mL urine) range of analysis (ng/mL urine)
SFN 1 1–0.05 5–100 5–80000
SFN-GSH 6 50 0.6 0.6–80
SFN-Cys-Gly 1 50 0.1 0.1–80
SFN-Cys 6 1–0.05 30–600 30–80000
SFN-NAC 3 1–0.05 15–300 15–80000