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. 2010 Dec 21;39(8):3224–3239. doi: 10.1093/nar/gkq1289

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© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Model of evolutionary history of Arxes (adipocyte-related X-chromosome expressed sequences) loci. Schematic of the ‘phylogeny’ of the Arxes genes based on bioinformatic analyses. Only one Arxes-like gene can be found on the rabbit x-chromosome while mouse and rat contain two paralog regions adjacent to each other on the x-chromosome. Arxes genes exhibit intact open reading frames. Target site duplication (TSD) sequences are given for mouse. A paralog stretch longer than the retrotransposed sequence (Arxes CDS including ∼800 bp upstream and 50 bp downstream) suggests a segmental duplication event.