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. Author manuscript; available in PMC: 2011 Apr 27.
Published in final edited form as: Mod Pathol. 2008 May 16;21(8):979–991. doi: 10.1038/modpathol.2008.76

Table 2.

Summarizing expression status of PIG-U/PIG-T/GPAA1/GPI8/PIG-S protein among most common cancer types and corresponding normal tissuesa

Tissue PIG-U
PIG-T
GPAA1
GPI-8
PIG-S
+++ (%) ++ (%) + (%) −ve(%)/P** +++ (%) ++ (%) + (%) −ve (%)/P +++ (%) ++ (%) + (%) −ve (%)/P +++ (%) ++ (%) + (%) −ve (%)/P +++ (%) ++ (%) + (%) −ve (%)/P
Stomach (T) 65 30 5 — 6 72 22 — 50 40 — 10 — 26 58 16 — 55 15 30
Stomach (N) 25 75 — — 100 — — — — 100 — — — 100 — — 25% 75 — —
Skin (T) 31 59 10 — — 68 32 — 11 57 25 7 — 7 61 32 — 34 52 14
Skin (N) — 100 — — — 100 — — 40 40 20 — — — 100 — — 20 80 —
Prostate (T) 35 41 24 — 6 82 12 — 6 35 47 12 — 18 53 29 — 24 24 52
Prostate (N) — 50 50 — — 50 50 — — — 50 50 — — 50 50 — 100 — —
Ovary (T) 55 35 10 — 7 50 43 — 15 45 30 10 10 54 33 3 — 69 28 3
Ovary (N) — 40 60 —/P =0.007 — 20 40 40 — — 60 40/P =0.011 — — 50 50/P =0.015 — 80 20 —
Breast (T) 30 59 7 4 50 43 7 — 19 39 26 16 3 38 38 21 — 80 20 —
Breast (N) 11 33 23 33/P =0.005 — 89 11 — 44 — 44 12 — 11 33 56 — 50 50 —
Testis (T) — 63 37 — 24 70 6 — — 32 53 15 5 17 67 11 — 22 78 —
Testis (N) — 50 50 — — 100 — — — — 100 — — 50 50 — — 50 50 —
Colon (T) 50 33 17 — 12 76 12 — 18 47 35 — 11 53 36 — 5 90 5 —
Colon (N) 20 80 — — — 20 80 —/
P =0.003 — 100 — — 40 60 — —/P<0.001 — 100 — —
Bladder (T) 5 58 37 — 18 53 29 — — 44 50 6 — 5 69 26 — 94 6 —
Bladder (N) — 67 33 — — 75 — 25 — 25 75 — — — 75 25/P<0.001 — 75 25 —
Uterus (T) 70 30 — — — 40 40 20 10 65 25 — 11 56 33 — 70 20 10 —
Uterus (N) 20 80 — — — — 100 — 20 20 60 — — — 100 —/P =0.015 60 40 — —
Thyroid (T) 45 50 5 — 45 55 — — 25 40 30 5 40 5 45 10 5 60 35 —
Thyroid (N) — 60 40 — — 40 60 —/P =0.001 — — 80 20/P =0.009 — 20 80 — — — 100 —/P =0.001
Lung (T) 10 40 50 — 13 73 10 4 3 37 50 10 — 10 87 3 — 30 70 —
Lung (N — 75 25 — — — 100 —/P =0.001 — — 80 20 — — 20 80 — — 100 —
Lymph node (T) — 37 53 10 — 15 75 10 — 10 50 40 — 5 60 35 — 16 84 —
Lymph node (N) — — — 100/
P<0.001 — — 100 — — — 67 33 — — — 100/P<0.001 — 11 89 —
Liver (T) 11 84 5 — 26 74 — — — 74 26 — 11 21 68 — — 65 35 —
Liver (N) 20 80 — — — 100 — — — 100 — — — 75 25 —/P<0.001 — 60 — 40
Pancreas (T) 5 90 5 — 25 65 10 — 5 55 35 5 — 5 80 15 10 75 15 —
Pancreas (N — 100 — — 20 — 80 —/P =0.001 — 80 — 20 — 100 — — — 60 20 20
Kidney (T) 16 53 31 — 44 37 19 — 5 32 47 16 5 5 75 15 10 53 37 —
Kidney (N) — 100 — — 100 — — — 100 — — — 100 — — — 20 60 — 20
a

The intensity of immunostaining was scored as follows: (−ve), no detectable immunostaining or basal immunostaining in <10% cells; (+), mild immunostaining in 10–30% cells; (++), moderate immunostaining in 30–50% cells and (+++), intense immunostaining in >50% of the cells showing cytoplasmic staining.

**

P indicates statistical significance of expression when <0.05.