Table 4.
Expression of PIG-U/PIG-T/GPAA1/GPI8/PIG-S protein in lung cancer vs normala
| Squamous cell carcinoma
|
Adenocarcinoma
|
Large cell carcinoma
|
Small cell carcinoma
|
Nonmalignant control
|
||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| +++ (%) | ++ (%) | + (%) | −ve | +++ (%) | ++ (%) | + (%) | −ve | +++ (%) | ++ (%) | + (%) | −ve (%) | +++ | ++ (%) | + (%) | −ve (%) | +++ | ++ (%) | + (%) | −ve (%) | |
| PIG-U | — | 10 | 90 | — | — | 80 | 20 | — | 60 | 40 | — | — | — | 20 | 80 | — | — | 75 | 25 | — |
| PIG-T | 20 | 80 | — | — | 20 | 80 | — | — | — | 100 | — | — | — | 20 | 60 | 20 | — | — | 100 | — |
| GPAA1 | — | 40 | 60 | — | 10 | 60 | 30 | — | — | — | 40 | 60 | — | 20 | 80 | — | — | — | 80 | 20 |
| GPI8 | — | — | 100 | — | — | 20 | 80 | — | — | — | 100 | — | — | 20 | 60 | 20 | — | — | 20 | 80 |
| PIG-S | — | 10 | 90 | — | — | 30 | 70 | — | — | 80 | 20 | — | — | 20 | 80 | — | — | — | 100 | — |
The intensity of immunostaining was scored as follows: (−ve), no detectable immunostaining or basal immunostaining in <10% cells; (+), mild immunostaining in 10–30% cells; (++), moderate immunostaining in 30–50% cells and (+++), intense immunostaining in >50% of the cells showing cytoplasmic staining.