Table 5.
Expression of GPI8 protein in bladder, colon and liver cancers
| Cancer type | Grade | Number of matched sample analyzed | Expression of GPI8a |
|
|---|---|---|---|---|
| Normal | Tumor | |||
| Bladder | I | 5 | +++ | + |
| II | 5 | +++ | + | |
| III | 5 | +++ | + | |
| Colon | I | 5 | ++ | + |
| II | 5 | ++ | + | |
| III | 5 | ++ | + | |
| Liver | I | 2 | +++ | + |
| II | 2 | +++ | + | |
Immunohistochemical detection of GPI8 expression in matched normal and tumor samples from bladder, colon and liver cancer at different histological grades. I, well-differentiated carcinoma; II, moderately differentiated carcinoma; III, poorly differentiated carcinoma. Significant loss of GPI8 expression was observed (P<0.001) in the tumor compared to the corresponding normal tissue.