Table 2.
Genes Most Highly Upregulated in Good Prognosis Tumors
| Gene Abbreviation | Gene's Full Name |
|---|---|
| ALDH1A1 | Aldehyde dehydrogenase 1 family, member A1 |
| AMICA1 | Adhesion molecule, interacts with CXADR antigen 1 |
| BHLHE41 | Basic helix-loop-helix family, member e41 |
| CCL19 | Chemokine (C-C motif) ligand 19 |
| CCR2 | Chemokine (C-C motif) receptor 2 |
| CD8a | CD8a molecule |
| CGA | Glycoprotein hormones, alpha polypeptide |
| CHI3L1 | Chitinase 3-like 1 |
| CHIT1 | Chitinase 1 |
| CHRNA9 | Cholinergic receptor, nicotinic, alpha 9 |
| FAM46C | Family with sequence similarity 46, member C |
| FBP1 | Fructose-1,6-bisphosphatase 1 |
| GZMA | Granzyme A |
| GZMB | Granzyme B |
| GZMH | Granzyme H |
| GZMK | Granzyme K |
| HLA-DPA1 | Major histocompatibility complex, class II, DP alpha 1 |
| HLA-DRB5 | Major histocompatibility complex, class II, DR beta 5 |
| IGJ | Immunoglobulin J polypeptide |
| IGKC | Immunoglobulin kappa constant |
| ITGBL1 | Integrin, beta-like 1 |
| KLRK1 | Killer cell lectin-like receptor subfamily K, member 1 (NKG2D) |
| LYZ | Lysozyme |
| MMP7 | Matrix metallopeptidase 7 |
| POU2AF1 | POU class 2 associating factor 1 |
| PROM1 | Prominin 1 |
| SLAMF1 | Signaling lymphocytic activation molecule family member 1 |
| TMEM200A | Transmembrane protein 200A |
| TNFRSF17 | Tumor necrosis factor receptor superfamily, member 17 |
| TRBC1 | T cell receptor beta constant 1 |
NOTE. The 30 genes in cluster bin 3 (Fig 1) most highly upregulated in good prognosis patients as compared with poor prognosis patients are listed in alphabetical order. Fold overexpression ranged from five- to 13-fold.