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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Expert Opin Drug Discov. 2011 Feb;6(2):109–127. doi: 10.1517/17460441.2011.547189

Figure 3.

Figure 3

Double labeling for the striatal vesicular Glu transporter-1 (VGLUT-1) and Glu immuno-gold. Electron photomicrograph using the diaminobenzidine technique to localize VGLUT-1 (dark reaction product) and the immunogold technique to localize an antibody against the neurotransmitter, Glu, within the dorsolateral striatum. Within the VGLUT-1 labeled nerve terminal (LT), there is an accumulation of small round synaptic vesicles and 10 nm gold particles indicating the location of the antibody (arrowhead). There is also an unlabeled nerve terminal (UT). The nerve terminals are making an asymmetrical synaptic contact (arrow) with an underlying dendritic spine (DS) or dendrite (DEND).