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. 2011 May;21(5):798–810. doi: 10.1101/gr.111385.110

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Copyright © 2011 by Cold Spring Harbor Laboratory Press

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Figure 6. — A stem/progenitor transition miRNA signature predicts the functional properties of mutant stem/progenitor cells. (A) A stem/progenitor transition miRNA signature that is predictive of stem or progenitor identity/property of mutant stem/progenitor cells was identified from the miRNAs that were concordantly regulated during stem to progenitor transition in muscle and blood by using PAM analyses (FDR < 0.001). Hierarchical clustering analyses showed that the 12 stem/progenitor transition miRNAs predict the functional properties of mutant stem/progenitor cells: (B) KSL-PTEN; (C) KSL-ETO; (D) KSL-RbTKO; and (E) MLL-LSC. False color scale depicts relative changes in expression.