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. 2011 May;21(5):798–810. doi: 10.1101/gr.111385.110

Figure 7.

Figure 7.

Effects of SPT-miRNAs on ES cell self-renewal and HSC reconstitution. (A) Schematics depicting a competition assay for examining the effects of miRNAs on ES cell self-renewal. (B,C) Relative ratios of miRNA-infected ES cells in a competition assay (n = 3, mean ± SD). (D) Schematics depicting a competition assay for examining the effects of miRNAs on HSC reconstitution. Vector-specific TaqMan qPCR primers and probes were used to determine the relative levels of the miRNA viral integrations relative to that of control viral vector integration. (E) Relative ratios of miRNA-infected cells in a competitive bone marrow transplantation assay (n = 5). Results from individual recipients at various time points (within 5%–95% distribution) after transplantation are shown, and median values of all recipients (horizontal lines) are indicated.