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. 2011 May;337(2):503–512. doi: 10.1124/jpet.110.177220

Fig. 4.

Fig. 4.

Extent of formation of active metabolites represented as total amount of active metabolite recovered in perfusate, liver, and bile as a percentage of the initial amount of prodrug added to the perfusate reservoir from isolated perfused rat liver experiments (A; mean ± S.D., n = 5 livers) and total amount of active metabolite recovered in medium, cells, and bile as a percentage of the initial amount of prodrug added to the culture medium from sandwich-cultured rat hepatocyte experiments (B; mean ± S.D., n = 2 livers in duplicate). *, p < 0.05 versus furamidine (two-tailed Student's t test).