TABLE 1.
Prodrug | Hepatic Clearance |
EH | ||
---|---|---|---|---|
Total | Metabolic | Biliary | ||
ml/min | ||||
Pafuramidine | 17.6 | 17.6 | <0.1 | 0.88 |
CPD-0868 | 12.4 | 12.4 | <0.1 | 0.62 |
Prodrug | Hepatic Clearance |
EH | ||
---|---|---|---|---|
Total | Metabolic | Biliary | ||
ml/min | ||||
Pafuramidine | 17.6 | 17.6 | <0.1 | 0.88 |
CPD-0868 | 12.4 | 12.4 | <0.1 | 0.62 |