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. 2011 May;337(2):487–493. doi: 10.1124/jpet.111.179317

Fig. 5.

Fig. 5.

Experiment 5: 100 mg/kg NAC during abstinence. A, time course for experiment 5. NAC (100 mg/kg) treatment occurred daily during abstinence and on cue and cue + cocaine-primed reinstatement testing. Rats were retested after 2 weeks of abstinence without NAC. B, relapse of cocaine seeking by cues or cues + cocaine. *, reduced responding by NAC treatment relative to saline treatment; p < 0.05. C, cocaine seeking at 2 weeks after discontinuation of NAC treatment. *, reduced responding by NAC treatment relative to saline treatment; p < 0.05. Sal, saline; VEH, vehicle.